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Trace Metals and Infectious Diseases (Strüngmann Forum Reports Book 16)


  

by: Jerome O. Nriagu, Eric P. Skaar, Joseph Lemire, Trevor F. Moraes, Vahid Fa Andisi, Anthony B. Schryvers, Michael A. Bachman, Jeffrey N. Weiser, Slade A. Loutet, Anson C. K. Chan, Maribel Navarro, Marek J. Kobylarz, Meghan M. Verstraete, Stephanie Pfaffen, Bin Ye, Angele L. Arrieta, Michael E. P. Murphy, James A. Imlay, Fudi Wang, Andreas Matusch, Lihong Zhang, Jennifer S. Cavet, Robert D. Perry, Sascha Brunke, Heran Darwin, Carol A. Fierke, Dennis J. Thiele, Inga Wessels, Günter Weiss, Gonzalo Visbal, George V. Dedoussis, Dieter Rehder, Robert E. Black, Victor J. DiRita, Lothar Rink, Miguel Che Parreira Soares, Tamara García-Barrera, Jozef M. Pacyna, Kyrre Sundseth, Elisabeth G. Pacyna, Mian Wang, Wenwen Liu, Thomas J. Webster, M. Leigh Ackland, Ellen K. Silbergeld, Julia Bornhorst, Rodney R. Dietert, John M. Pettifor, Peter-Leon Hagedoorn, Anca-Maria Oros-Peusquens, J. Sabine Becker, Wolfgang Maret, Joseph Caruso, Christopher H. Contag, David P. Giedroc, Richard B. Thompson, Julia Lupp

Trace Metals and Infectious Diseases (Strüngmann Forum Reports Book 16)










Binding: Kindle Edition
Edition: 1
Format: Kindle eBook
Label: The MIT Press
Languages: EnglishPublished
Manufacturer: The MIT Press
Number Of Pages: 504
Publication Date: May 08, 2015
Publisher: The MIT Press
Release Date: May 08, 2015
Studio: The MIT Press




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Experts explore the influence of trace metals on the pathogenesis of infectious diseases.



Many parts of the world in which common infectious diseases are endemic also have the highest prevalence of trace metal deficiencies or rising rates of trace metal pollution. Infectious diseases can increase human susceptibility to adverse effects of metal exposure (at suboptimal or toxic levels), and metal excess or deficiency can increase the incidence or severity of infectious diseases. The co-clustering of major infectious diseases with trace metal deficiency or toxicity has created a complex web of interactions with serious but poorly understood health repercussions, yet has been largely overlooked in animal and human studies. This book focuses on the distribution, trafficking, fate, and effects of trace metals in biological systems. Its goal is to enhance our understanding of the relationships between homeostatic mechanisms of trace metals and the pathogenesis of infectious diseases.



Drawing on expertise from a range of fields, the book offers a comprehensive review of current knowledge on vertebrate metal-withholding mechanisms and the strategies employed by different microbes to avoid starvation (or poisoning). Chapters summarize current, state-of-the-art techniques for investigating pathogen-metal interactions and highlight open question to guide future research. The book makes clear that improving knowledge in this area will be instrumental to the development of novel therapeutic measures against infectious diseases.



Contributors
M. Leigh Ackland, Vahid Fa Andisi, Angele L. Arrieta, Michael A. Bachman, J. Sabine Becker, Robert E. Black, Julia Bornhorst, Sascha Brunke, Joseph A. Caruso, Jennifer S. Cavet, Anson C. K. Chan, Christopher H. Contag, Heran Darwin, George V. Dedoussis, Rodney R. Dietert, Victor J. DiRita, Carol A. Fierke, Tamara Garcia-Barrera, David P. Giedroc, Peter-Leon Hagedoorn, James A. Imlay, Marek J. Kobylarz, Joseph Lemire, Wenwen Liu, Slade A. Loutet, Wolfgang Maret, Andreas Matusch, Trevor F. Moraes, Michael E. P. Murphy, Maribel Navarro, Jerome O. Nriagu, Ana-Maria Oros-Peusquens, Elisabeth G. Pacyna, Jozef M. Pacyna, Robert D. Perry, John M. Pettifor, Stephanie Pfaffen, Dieter Rehder, Lothar Rink, Anthony B. Schryvers, Ellen K. Silbergeld, Eric P. Skaar, Miguel C. P. Soares, Kyrre Sundseth, Dennis J. Thiele, Richard B. Thompson, Meghan M. Verstraete, Gonzalo Visbal, Fudi Wang, Mian Wang, Thomas J. Webster, Jeffrey N. Weiser, Günter Weiss, Inga Wessels, Bin Ye, Judith T. Zelikoff, Lihong Zhang





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